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    Methoxy PEG Propionaldehyde

    产品代号：

    M-PEG-ALD

    产品纯度：

    ≥ 95%

    包装规格：

    1g, 10g, 100g等（特殊包装需收取分装费用）

    分子量：

    5000 Da-40000 Da，等

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    科研客户小批量一键采购地址（小于5克）

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    • 产品描述
    • 参考文献

    • 　　甲氧基聚乙二醇丙醛是一个N-端氨基反应的聚乙二醇活性衍生物。可对蛋白、多肽或其他生物仿制品中的氨基进行定点修饰，条件温和在PH=5-8还原剂存在下即可进行。

      　　PG电子提供M-ALD分子量的5000 Da，10000 Da，20000 Da，30000 Da，40000 Da 的产品1克和10克包装。

      　　PG电子提供分装服务，需要收取分装费用，如果您需要分装为其他规格请与我们联系。

      　　PG电子同时提供其他分子量的M-ALD产品，如你需要请与我司sales@huaqiangcn.com联系。

      　　PG电子提供大批量生产产品及GMP级别产品，如需报价请与我们联系.

       

       

    • References:

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      4. Cheng, Y., et al., Doxorubicin Loaded Tumor-Triggered Targeting Ammonium Bicarbonate Liposomes for Tumor-Specific Drug Delivery, Colloids and Surfaces B: Biointerfaces, 2019.
      5. Gertler, A., et al., Pegylated Human Leptin D23L Mutant–Preparation and Biological Activity In Vitro and in Vivo in Male ob/ob Mice, Endocrinology, 2019.
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      17. Mayolo-Deloisa, K., et al., Aldehyde PEGylation of laccase from Trametes versicolor in route to increase its stability: effect on enzymatic activity, Journal of Molecular Recognition, 2015, 28(3): 173-179.
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      26. Pink, A., et al., Purification, characterization and plasma half-life of PEGylated soluble recombinant non-HA-binding CD44, BioDrugs, 2014, 28(4) p:393-402.
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      28. Li, R., et al., Preparation and Characterization of Biological Non-toxic Hybrid Nanoparticles Based on Lactide and Poly(ethylene glycol) Loading Docetaxel for Anticancer Drug Delivery, Chinese Journal of Chemical Engineering, 2014, 22:11–12, P. 1357-1362.
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      30. Mu Q, et al., Molecular Insight into the Steric Shielding Effect of PEG on the Conjugated Staphylokinase: Biochemical Characterization and Molecular Dynamics Simulation, PLoS ONE, 2013, 8(7): e68559.
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      40. Top, A., et al., Conformational and Aggregation Properties of a PEGylated Alanine-Rich Polypeptide, Biomacromolecules, 2011, 12(6), pp 2184–2192.
      41. Wang, J., et al., Kinetic and stoichiometric analysis of the modification process for N-terminal PEGylation of staphylokinase, Analytical Biochemistry, 2011, 412: 1, P. 114-116.
      42. Gonzalez-Valdez, J., et al., Potential application of aqueous two-phase systems for the fractionation of RNase A and α-Lactalbumin from their PEGylated conjugates, J. Chem. Technol. Biotechnol., 2011, 86: 26–33.
      43. Wang, Y-J., et al., PEGylation markedly enhances the in vivo potency of recombinant human non-glycosylated erythropoietin: A comparison with glycosylated erythropoietin, Journal of Controlled Release, 2010, 145:3, p. 306-313.
      44. Elinav, E., et al., Pegylated Leptin Antagonist Is a Potent Orexigenic Agent: Preparation and Mechanism of Activity, Endocrinology, 2009, 150(7), 3083–3091.
      45. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Scientific_Discussion/human/000420/WC500025941.pdf.
      46. Kateja, N., et al., Development of an integrated continuous PEGylation and purification Process for granulocyte colony stimulating factor, Journal of Biotechnology, 2020, 322, p. 79-89.
      47. Hebbi, V., et al., Process analytical technology application for protein PEGylation using near infrared spectroscopy: G-CSF as a case study, Journal of Biotechnology, 2021, 325, P. 303-311.

      48. Luo, S., et al., A new site-specific monoPEGylated β-lactoglobulin at the N-terminal: Effect of different molecular weights of mPEG on its conformation and antigenicity, Food Chemistry, 2021, 343, 128402.

      49. Tao, Y., et al., MiR-1909-5p targeting GPX4 affects the progression of aortic dissection by modulating nicotine-induced ferroptosis, Food and Chemical Toxicology, 2024, V. 191. Keywords: Aortic dissection; Nicotine; Endothelial cells; miR-1909-5p; GPX4; Methoxy PEG propionaldehyde

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